[Adenovirus conjunctivitis diagnosis using RPS Adenodetector]

Arq Bras Oftalmol. 2007 May-Jun;70(3):441-4. doi: 10.1590/s0004-27492007000300010.
[Article in Portuguese]

Abstract

Purpose: To evaluate the RPS Adenodetector, a rapid immunochromatographic test, in the diagnosis of patients with clinical overt adenoviral conjunctivitis.

Methods: Consecutive case series. Patients underwent conjunctiva scraping for RPS Adenodetector test and culture to identify adenovirus.

Results: A total of 11 patients were studied, and 10 had unilateral disease. Five (45.5%) had symptoms for 2 days, 5 for three days, and 1 for 7 days. Adenovirus culture was positive in 8 patients (73%) and RPS Adenodetector was positive in 9 (82%) patients. Eight patients had adenovirus identification by both methods. In one patient the RPS Adenodetector was positive in contrast to a negative culture. The two patients revealing negative RPS Adenodetector results also had negative cultures. The sensitivity was 100% and the specificity was 67%.

Conclusion: The RPS Adenodetector is a useful tool in the rapid diagnosis of adenovirus conjunctivitis and may contribute to the spread control of this highly contagious disease.

Publication types

  • Evaluation Study

MeSH terms

  • Adenovirus Infections, Human / diagnosis*
  • Adenovirus Infections, Human / virology
  • Adenoviruses, Human / immunology
  • Adenoviruses, Human / isolation & purification*
  • Adolescent
  • Adult
  • Antigens, Viral / analysis
  • Conjunctivitis, Viral / diagnosis*
  • Conjunctivitis, Viral / virology
  • Diagnostic Techniques, Ophthalmological*
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity
  • Virus Cultivation

Substances

  • Antigens, Viral
  • Reagent Kits, Diagnostic