Holding a slipping object in hand requires adjustment of grip forces. The aim of the study was to develop a method for measuring the temporal and spatial distribution of grip forces during the holding of a slipping object in the hand. A special grip rod with a measuring film containing 200 resistor-based pressure sensors equally distributed over 50 cm(2) was developed, providing a system that has a spatial resolution of 5 mm, a temporal resolution of 1/150 Hz and a force resolution 0.05 N. A force-change-detection algorithm was constructed to detect and separate pressure and position of individual fingers. The algorithm is a modification of a classical Gaussian random field theory algorithm for detecting significant data [Rogerson PA. Change detection thresholds for remotely sensed images. J Geog Syst 2002;4:85-97]. The modification takes the signal strength into account to reduce false positive detection in low grip force situations. The grip force measuring system and the force-change-detection algorithm allow measurement of the forces exerted by any number of fingers simultaneously without any constraints on finger position and are suitable for basic and clinical research in human and animal physiology as well as for psychophysics studies.