Clinical and microbiologic changes associated with the combined use of a powered toothbrush and a triclosan/copolymer dentifrice: a 3-year prospective study

J Periodontol. 2007 Sep;78(9):1708-17. doi: 10.1902/jop.2007.070028.

Abstract

Background: Different means are available for self-performed oral hygiene. The aim of this study was to evaluate the clinical and microbiologic effects of a preventive homecare program including the combined use of a powered toothbrush and a triclosan/copolymer-containing dentifrice.

Methods: A total of 160 adult subjects without signs of destructive periodontal disease were recruited for this 3-year randomized controlled trial. The subjects were assigned to a homecare program using an oscillating/rotating powered toothbrush and a triclosan/copolymer/fluoride-containing dentifrice (test) or a manual toothbrush and a standard fluoride-containing dentifrice (control). Supragingival polishing and reinforcement of homecare procedures were provided every 6 months. Plaque, bleeding on probing (BOP), and probing depth (PD) were scored at baseline and after 1, 2, and 3 years. Subgingival plaque samples were taken from the mesial aspect of each tooth at baseline and after 1, 2, and 3 years and were analyzed for their content of 40 bacterial species using checkerboard DNA-DNA hybridization. All data analyses were based on "intention-to-treat" with the subject as the statistical unit.

Results: Compared to baseline, no significant changes in clinical parameters were observed during the 3 years, except for a reduction in the mean PD at the 2- and 3-year follow-up examinations (P <0.05). No significant differences were found between the two groups with regard to plaque, BOP, or PD or in the mean counts of the 40 species at any time point.

Conclusion: The study failed to prove additional benefits of the combined use of a powered toothbrush and a triclosan/copolymer-containing dentifrice in adult subjects without signs of destructive periodontal disease.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Colony Count, Microbial
  • Complex Mixtures / therapeutic use
  • DNA, Bacterial / analysis
  • Dental Devices, Home Care
  • Dental Plaque / microbiology*
  • Dental Plaque / prevention & control
  • Dentifrices / therapeutic use*
  • Electricity
  • Female
  • Fluorides / therapeutic use
  • Gingival Pocket / microbiology*
  • Gingival Pocket / therapy
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Regression Analysis
  • Silicic Acid
  • Single-Blind Method
  • Toothbrushing / instrumentation*
  • Toothpastes
  • Treatment Outcome
  • Triclosan / therapeutic use

Substances

  • Complex Mixtures
  • DNA, Bacterial
  • Dentifrices
  • Toothpastes
  • hydrated silica gel-based toothpaste
  • Silicic Acid
  • Triclosan
  • Fluorides