Ki-67 is expressed in multiplying forms of Schistosoma mansoni, but not in snail host tissues

Mem Inst Oswaldo Cruz. 2007 Aug;102(5):651-3. doi: 10.1590/s0074-02762007005000063.

Abstract

Ki-67 is a protein expressed in the nucleus of several species during cell-division, being absent during the GO resting phase of the cellular cycle. During attempts to disclose mitosis in the so-called " amebocyte-producing organ " in Biomphalaria glabrata infected with Schistosoma mansoni, the parasite multiplying forms appeared strongly marked for Ki-67, while the snail tissues were completely negative. These data are worth registering to complement general data on Ki-67, and to help future studies on the relationship of the parasite and of its intermediate host.

MeSH terms

  • Animals
  • Biomphalaria / cytology*
  • Biomphalaria / parasitology
  • Hemocytes / chemistry
  • Host-Parasite Interactions / physiology
  • Immunohistochemistry
  • Ki-67 Antigen / metabolism*
  • Mice
  • Mitotic Index
  • Schistosoma mansoni / physiology*
  • Staining and Labeling

Substances

  • Ki-67 Antigen