Abstract
A 40-year-old, HIV-infected female patient received antibiotic treatment for a urinary tract infection. After the initial success of therapy and a symptom-free period, she developed pneumonia with septic shock and adult respiratory distress syndrome (ARDS). In spite of intensive care and respirator therapy with positive end-expiratory pressure (PEEP), she died of infectious toxic shock. Autopsy findings showed relapsing, gram-negative, bacterial pneumonia (morphologically compatible with Klebsiella pneumonia) and secondary, invasive aspergillosis. The pathogenesis and epidemiology of these unusual complications of AIDS are discussed.
MeSH terms
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AIDS-Related Complex / diagnosis
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AIDS-Related Complex / pathology
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Adult
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Aspergillosis, Allergic Bronchopulmonary / diagnosis*
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Aspergillosis, Allergic Bronchopulmonary / pathology
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Aspergillus fumigatus* / ultrastructure
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Brain / pathology
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Diagnosis, Differential
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Female
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HIV Infections / complications*
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HIV Infections / diagnosis
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HIV Infections / pathology
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Humans
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Klebsiella Infections / diagnosis*
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Klebsiella Infections / pathology
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Lung / pathology
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Lung Abscess / pathology
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Opportunistic Infections / diagnosis*
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Opportunistic Infections / pathology
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Pneumonia / diagnosis*
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Pneumonia / pathology
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Respiratory Distress Syndrome / pathology