Abstract
Human enteroviruses are currently grouped into five species Human enterovirus A (HEV-A), HEV-B, HEV-C, HEV-D and Poliovirus. During surveillance for enteroviruses serologically non-typable enterovirus strains were found from acute flaccid paralysis patients and healthy individuals. In this study, we report isolates of recently described enterovirus types EV76 and EV90 of HEV-A species and characterize two new enterovirus type candidates, EV96 and EV97, to species HEV-C and HEV-B, respectively. Analysis of partial 3D regions of EV96 strains revealed sequence divergence consistent with several recombination events between EV96, other HEV-C viruses and polioviruses. Phylogenetic analysis of all available 5'-untranslated region sequences of human entero- and rhinovirus prototype strains and 10 simian enterovirus strains suggested interspecies recombination involving this region.
MeSH terms
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5' Untranslated Regions / genetics*
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DNA, Viral / chemistry
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DNA, Viral / genetics
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Enterovirus A, Human / classification*
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Enterovirus A, Human / genetics*
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Enterovirus A, Human / isolation & purification
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Evolution, Molecular*
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Humans
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Molecular Sequence Data
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Phylogeny
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Rhinovirus / classification
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Rhinovirus / genetics
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Serotyping
Substances
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5' Untranslated Regions
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DNA, Viral
Associated data
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GENBANK/EF364396
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GENBANK/EF364397
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GENBANK/EF364398
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GENBANK/EF364399
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GENBANK/EF364400
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GENBANK/EF364401
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GENBANK/EF364402
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GENBANK/EF364403
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GENBANK/EF364404
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GENBANK/EF364405
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GENBANK/EF364406
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GENBANK/EF364407
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GENBANK/EF364408
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GENBANK/EF364409
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GENBANK/EF364410
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GENBANK/EF364411
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GENBANK/EF364412
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GENBANK/EF364413
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GENBANK/EF364414
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GENBANK/EF364415
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GENBANK/EF364416
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GENBANK/EF364417
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GENBANK/EF364418
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GENBANK/EF364419
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GENBANK/EF364420
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GENBANK/EF364421
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GENBANK/EF364422
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GENBANK/EF364423
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GENBANK/EF392677