Use of recombinant factor VIIa in a preterm infant with coagulopathy and subdural hematoma

J Matern Fetal Neonatal Med. 2007 Aug;20(8):627-9. doi: 10.1080/14767050701411935.

Abstract

Activated recombinant factor VIIa was administered to a preterm infant with bleeding diasthesis and a huge subdural hematoma that could not be controlled by the blood products. The coagulation tests were normalized the following day. Recombinant factor VIIa can be a choice in selected cases with intractable bleedings unesponsive to conventional replacement therapy.

Publication types

  • Case Reports

MeSH terms

  • Blood Component Transfusion
  • Cerebral Hemorrhage / therapy*
  • Factor VII / therapeutic use*
  • Factor VIIa
  • Hematoma, Subdural / therapy*
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / therapy*
  • Male
  • Plasma
  • Recombinant Proteins / therapeutic use

Substances

  • Recombinant Proteins
  • Factor VII
  • recombinant FVIIa
  • Factor VIIa