Since 2002 19 laparoscopic adrenalectomies with a lateral transperitoneal access have been performed at our Division of Surgery. Three patients had Conn's syndrome, 8 incidentaloma, 4 pheochromocytoma, 2 Cushing's syndrome, 1 metastases from a contralateral renal cancer and 1 metastases from lung cancer. The parameters considered for data analysis were: intra- and postoperative hypertensive crises, haemorrhage, subcutaneous emphysema, conversions, dura- tion of surgery, hospital stay, postoperative comfort, and canalisation and mobilisation times. The results obtained in our experience were comparable to those reported in the literature, confirming the reproducibility and feasibility of this type of surgical procedure. Comparison of the data obtained with laparoscopic, surgery and those obtained with traditional surgical treatment suggest that it is reasonable to claim that the laparoscopic approach is today the gold standard for adrenal surgery.