Background and purpose: South Asians are the most prevalent ethnic group in the world. Intracranial disease is the most common vascular lesion worldwide.
Methods: We prospectively studied 200 consecutive ethnic South Asian patients with acute ischemic stroke in Singapore.
Results: Intracranial large-artery disease was prevalent among 54% of all stroke subtypes and was independently associated with hypertension and higher serum erythrocyte sedimentation rate.
Conclusions: Among ethnic South Asian patients with ischemic stroke, intracranial large arteries are the predominant site of disease.