Abstract
We report the development of invasive pulmonary aspergillosis in a patient treated for acute myeloid leukaemia during empirical voriconazole therapy for febrile neutropenia. The patient failed to respond to the institution of salvage combination therapy with amphotericin B and voriconazole, but survived after adjunctive surgical resection.
MeSH terms
-
Acute Disease
-
Antifungal Agents / therapeutic use*
-
Aspergillosis / drug therapy
-
Aspergillosis / surgery*
-
Drug Resistance, Fungal / drug effects*
-
Fever / microbiology
-
Humans
-
Leukemia, Myeloid / complications
-
Lung Diseases, Fungal / drug therapy
-
Lung Diseases, Fungal / surgery*
-
Male
-
Middle Aged
-
Neutropenia / microbiology
-
Pyrimidines / therapeutic use*
-
Triazoles / therapeutic use*
-
Voriconazole
Substances
-
Antifungal Agents
-
Pyrimidines
-
Triazoles
-
Voriconazole