The peripeduncular nucleus: a novel target for deep brain stimulation?

Neuroreport. 2007 Aug 6;18(12):1301-2. doi: 10.1097/WNR.0b013e3282638603.

Abstract

The pedunculopontine nucleus, a promising new target for deep brain stimulation in Parkinson's disease, straddles the pontomesencephalic junction--unfamiliar territory to most functional neurosurgeons. This contribution reviews the anatomy of the pedunculopontine and peripeduncular nuclei. Given the reported findings of Mazzone et al. in NeuroReport, the authors postulate that the peripeduncular nucleus might be of previously unexpected clinical relevance.

Publication types

  • Comment
  • Letter

MeSH terms

  • Anatomy, Artistic
  • Electric Stimulation Therapy / methods
  • Electric Stimulation Therapy / standards*
  • Electric Stimulation Therapy / trends
  • Humans
  • Medical Errors / prevention & control*
  • Medical Illustration
  • Mesencephalon / anatomy & histology*
  • Mesencephalon / physiology
  • Neuronavigation / standards
  • Neuronavigation / trends
  • Parkinson Disease / therapy*
  • Pedunculopontine Tegmental Nucleus / anatomy & histology*
  • Pedunculopontine Tegmental Nucleus / physiology
  • Stereotaxic Techniques / standards*
  • Stereotaxic Techniques / trends