An N-aryl-substituted oxazolidinone-containing ketone-catalyzed asymmetric epoxidation with hydrogen peroxide as the primary oxidant

J Org Chem. 2007 Aug 3;72(16):6320-3. doi: 10.1021/jo0708644. Epub 2007 Jul 10.

Abstract

Asymmetric epoxidation of various olefins with an N-aryl-substituted oxazolidinone-containing ketone as catalyst and hydrogen peroxide as the primary oxidant has been investigated, and up to 96% ee was obtained.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Catalysis
  • Chemistry, Organic / methods*
  • Hydrogen Peroxide / chemistry*
  • Ketones / chemistry*
  • Magnetic Resonance Spectroscopy
  • Models, Chemical
  • Molecular Structure
  • Oxazolidinones / chemical synthesis*
  • Oxazolidinones / chemistry*
  • Oxidants / chemistry*
  • Oxidation-Reduction
  • Styrenes / chemistry
  • Time Factors

Substances

  • Ketones
  • Oxazolidinones
  • Oxidants
  • Styrenes
  • vinyltoluene
  • Hydrogen Peroxide