Abstract
Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amine Oxidase (Copper-Containing) / therapeutic use*
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Anaphylaxis / drug therapy*
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Asthma / drug therapy*
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Brain Ischemia / complications
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Brain Ischemia / drug therapy*
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Humans
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Hypersensitivity / drug therapy*
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Inflammation / drug therapy*
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Phytotherapy / methods
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Phytotherapy / trends
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Pisum sativum / enzymology*
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Plant Extracts / therapeutic use
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Practice Guidelines as Topic
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Practice Patterns, Physicians'
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Seeds / enzymology
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Shock / etiology
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Shock / prevention & control
Substances
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Plant Extracts
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Amine Oxidase (Copper-Containing)