Inhibitory activity against tobacco mosaic virus (TMV) replication of pinoresinol and syringaresinol lignans and their glycosides from the root of Rhus javanica var. roxburghiana

J Agric Food Chem. 2007 Aug 8;55(16):6460-5. doi: 10.1021/jf0709808. Epub 2007 Jul 6.

Abstract

Four new diepoxylignan glycosides, pinoresinol-4'-O-[6' '-O-(E)-feruloyl]-beta-D-glucopyranoside (1), pinoresinol-4'-O-[4' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (2), pinoresinol-4'-O-[3' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (3), and syringaresinol- 4'-O-[4' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (4), together with three known compounds, pinoresinol (5), syringaresinol (6), and pinoresinol-4'-O-beta-D-glucopyranoside (7), were isolated from the n-butanol extract of Rhus javanica var. roxburghiana, and their structures were established using various spectroscopic techniques. Three glycosides (2-4) of the lignans showed moderate inhibition of multiplication of the tobacco mosaic virus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Furans / pharmacology*
  • Glycosides / pharmacology
  • Lignans / pharmacology*
  • Plant Roots / chemistry*
  • Rhus / chemistry*
  • Tobacco Mosaic Virus / drug effects*
  • Virus Replication / drug effects*

Substances

  • Furans
  • Glycosides
  • Lignans
  • syringaresinol
  • pinoresinol