Abstract
HPV infections have become a major problem in immunocompromised patients, particularly in HIV-positive subjects. HPV lesions are observed more frequently in the ano-genital area and rarely in different body areas, such as the skin and oral cavity. However, in HIV-positive subjects there is an increased risk of oral condylomas. We describe the case of an HIV-positive Nigerian young woman, who came to our notice due to the appearance of small labial and mouth mucous membrane lesions, related to HPV infection, as shown by a biopsy. These lesions were not evident in the genital area. After two years in which the patient no longer received therapy, there was a progressive reduction in CD4 count, associated with the development of the oral condylomas. Hence the patient began a new HAART combination, but after seven months, although a slight improvement emerged in the CD4 count with the disappearance of HIV-RNA, there has been no regression of oral condylomas.
MeSH terms
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Adenine / administration & dosage
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Adenine / analogs & derivatives
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Adenine / therapeutic use
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Adult
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Alphapapillomavirus / isolation & purification*
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Anti-HIV Agents / therapeutic use
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Antiretroviral Therapy, Highly Active
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Deoxycytidine / administration & dosage
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Deoxycytidine / analogs & derivatives
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Deoxycytidine / therapeutic use
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Dideoxynucleosides / administration & dosage
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Dideoxynucleosides / therapeutic use
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Emtricitabine
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Female
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HIV Infections / complications*
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HIV Infections / drug therapy
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Humans
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Italy
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Lamivudine / administration & dosage
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Lamivudine / therapeutic use
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Lopinavir
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Mouth Mucosa / virology
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Nigeria / ethnology
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Organophosphonates / administration & dosage
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Organophosphonates / therapeutic use
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Papillomavirus Infections / complications*
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Pyrimidinones / administration & dosage
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Pyrimidinones / therapeutic use
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Ritonavir / administration & dosage
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Ritonavir / therapeutic use
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Sex Work*
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Stomatitis / complications
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Stomatitis / virology*
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Tenofovir
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Treatment Refusal
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Zidovudine / administration & dosage
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Zidovudine / therapeutic use
Substances
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Anti-HIV Agents
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Dideoxynucleosides
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Organophosphonates
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Pyrimidinones
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Deoxycytidine
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Lopinavir
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Lamivudine
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Zidovudine
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Tenofovir
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Emtricitabine
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Adenine
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Ritonavir
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abacavir