Clinical and histological evaluation of immediate-loaded posterior implants in nonhuman primates

Implant Dent. 2007 Jun;16(2):176-86. doi: 10.1097/ID.0b013e3180500a84.

Abstract

Purpose: To evaluate a square-thread design implant and compare the bone-implant contact percentage between immediate-loaded and nonloaded implants (controls) in nonhuman primates.

Materials: Five nonhuman primates each received 3 implants, with a total of 5 control implants and 10 immediate-loaded implants in posterior regions of the mouth. Ninety days after surgery (and function was appropriate), block sections of the implants were removed and sectioned in 200-mum thick pieces. The block sections were stained with modified Masson for evaluation of the bone-implant contact percentage.

Results: One of the immediate-loaded implants failed. The bone-implant contact percentage of control implants ranged from 50.34% to 64.13% and averaged 56.3%. The bone-implant contact percentage of immediate-loaded implants ranged from 43.23% to 75.72%, with an average of 62.4%. Two implants had lower bone-implant contact percentage than the others, and when these are not included in the evaluation, the bone-implant contact percentage average increased to 67.6%.

Conclusions: Immediate-loaded implants in the nonhuman primates often have a higher bone-implant contact percentage at 90 days than unloaded implants. The bone remodeling is different for loaded implant-bone interfaces than for unloaded conditions. However, 1 immediate-loaded implant failed, and 2 implants had lower bone-implant contact percentage than controls. Therefore, although there are benefits of immediate loading, there appear to also be some risks.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Bone Remodeling / physiology
  • Crowns
  • Dental Abutments*
  • Dental Implantation, Endosseous / methods*
  • Dental Implants*
  • Dental Prosthesis Design*
  • Dental Prosthesis, Implant-Supported
  • Dental Restoration Failure
  • Macaca fascicularis
  • Mandible / pathology
  • Mandible / physiopathology
  • Mandible / surgery
  • Osseointegration / physiology
  • Random Allocation
  • Single-Blind Method
  • Surface Properties
  • Time Factors

Substances

  • Dental Implants