Robust baseline correction algorithm for signal dense NMR spectra

J Magn Reson. 2007 Aug;187(2):288-92. doi: 10.1016/j.jmr.2007.05.008. Epub 2007 May 16.

Abstract

This paper outlines a fully automated algorithm for baseline correction. Based on our experience with NMR spectra of complex mixtures, this algorithm is designed to automatically differentiate signal points from baseline points. The algorithm's strength is its ability to accurately determine baseline points in very dense spectra, without destroying the line shapes of prominent peaks. The algorithm described is implemented in Chenomx NMR Suite 4.6. It is demonstrated here using two separate spectra acquired on two different NMR spectrometers.

MeSH terms

  • Acids / chemistry
  • Algorithms*
  • Artifacts
  • Calibration
  • Magnetic Resonance Spectroscopy / methods*
  • Magnetic Resonance Spectroscopy / standards
  • Plant Extracts / chemistry
  • Signal Processing, Computer-Assisted

Substances

  • Acids
  • Plant Extracts