Blindness and low vision in a tertiary ophthalmologic center in Thailand: the importance of cytomegalovirus retinitis

Retina. 2007 Jun;27(5):635-40. doi: 10.1097/01.iae.0000249575.38830.45.

Abstract

Purpose: To determine the causes of blindness and low vision in patients consulting a tertiary ophthalmologic center in northern Thailand.

Methods: The study population included 2,951 new consecutive patients from the Department of Ophthalmology at University Hospital in Chiang-Mai, Thailand. Main outcome measures were blindness and low vision, which were defined according to World Health Organization criteria.

Results: Of 2,951 patients, 369 (12.5%) had blindness and/or low vision (bilateral blindness in 73, unilateral blindness in 129, bilateral low vision in 77, and unilateral low vision in 90). Of the etiological causes of visual loss, age-related ocular disease was the most frequent (128 patients [35%]) followed by infections (66 patients [18%]) and trauma (43 patients [12%]). Although infections and trauma were the predominant causes of blindness, age-related disorders were frequently found in patients with low vision. Of anatomical sites, the lens (134 patients [36%]) was the main location of visual loss, closely followed by disorders of the retina and/or uvea (126 patients [34%]). Blindness and low vision were considered avoidable in 70% of cases. Of 73 patients with bilateral blindness, 14 had active cytomegalovirus retinitis, accounting for 19% of all patients with bilateral blindness.

Conclusion: The most common causes of blindness and low vision in a tertiary center in northern Thailand were age-related ocular disorders and infections, which were predominantly cases of cytomegalovirus retinitis in human immunodeficiency virus-infected patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • AIDS-Related Opportunistic Infections / epidemiology
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blindness / epidemiology*
  • Blindness / etiology
  • Child
  • Child, Preschool
  • Cytomegalovirus Retinitis / complications
  • Cytomegalovirus Retinitis / epidemiology*
  • Female
  • Hospitals, University / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Ophthalmology / statistics & numerical data*
  • Thailand / epidemiology
  • Vision, Low / epidemiology*
  • Vision, Low / etiology