[Blackwater fever in children during cerebral malaria: 3 case reports in Bamako]

Arch Pediatr. 2007 Aug;14(8):993-5. doi: 10.1016/j.arcped.2007.04.005. Epub 2007 May 23.
[Article in French]

Abstract

Background: Blackwater fever is a rare but serious form of malaria in children. Diagnosis relies on clinical symptoms and on the color of the urines.

Objectives: To describe blackwater fever in children, a disease whose prevalence seems to be increasing.

Method: We report 3 cases of blackwater fever observed in our institution.

Results: In 2 cases, acute renal insufficiency with oligoanuria was observed. In all the 3 cases, treatment with quinine was stopped and replaced by injectable artemether. Evolution was dependent on renal function, and included in 1 patient neurological sequels consisting in aphasia.

Conclusion: Blackwater fever is a severe affection whose diagnosis should be evoked using the color of urine. Evolution is usually favorable in the pediatric population, when adequate care can be provided.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / drug therapy
  • Acute Kidney Injury / parasitology
  • Antimalarials / therapeutic use
  • Artemether
  • Artemisinins / therapeutic use
  • Blackwater Fever / drug therapy
  • Blackwater Fever / parasitology*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Malaria, Cerebral / complications*
  • Malaria, Cerebral / drug therapy
  • Male
  • Mali
  • Oliguria / drug therapy
  • Oliguria / parasitology

Substances

  • Antimalarials
  • Artemisinins
  • Artemether