A FAScinating receptor in self-tolerance

Madhu Ramaswamy; Richard M Siegel

doi:10.1016/j.immuni.2007.05.004

A FAScinating receptor in self-tolerance

Immunity. 2007 May;26(5):545-7. doi: 10.1016/j.immuni.2007.05.004.

Authors

Madhu Ramaswamy¹, Richard M Siegel

Affiliation

¹ Immunoregulation Unit, Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD 20892, USA.

PMID: 17521581
DOI: 10.1016/j.immuni.2007.05.004

Abstract

In this issue of Immunity,Stranges et al. (2007) ablate expression of the death receptor Fas in T cells, B cells, and DC. Fas deficiency in any of these lineages is sufficient to break self-tolerance.

Publication types

Comment

MeSH terms

Animals
Antigen Presentation / immunology
Cell Death
Humans
Self Tolerance / immunology*
fas Receptor / immunology*

Substances

fas Receptor