Comparison of several commercial serologic kits and Em18 serology for detection of human alveolar echinococcosis

Diagn Microbiol Infect Dis. 2007 Sep;59(1):93-5. doi: 10.1016/j.diagmicrobio.2007.03.018. Epub 2007 May 16.

Abstract

The aim of this study was to design the best serologic strategy for diagnosing human alveolar echinococcosis (AE) cases in medical laboratory routine procedures. By combining 2 screening techniques, indirect hemagglutination with Em(2plus)-ELISA and/or recEm18-ELISA, 46 of 47 AE cases were detected. The necessary confirmation of results is then obtained by using immunoblot (LDBIO-IB and/or recEm18-IB).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Animals
  • Echinococcosis, Hepatic / diagnosis*
  • Echinococcosis, Hepatic / immunology
  • Female
  • Hemagglutination Tests / methods
  • Humans
  • Immunoassay / methods
  • Immunoblotting / methods
  • Male
  • Middle Aged
  • Reagent Kits, Diagnostic / parasitology
  • Sensitivity and Specificity
  • Serologic Tests / methods*

Substances

  • Reagent Kits, Diagnostic