"Crystal dex:" free-base dextromethorphan

J Emerg Med. 2007 May;32(4):393-6. doi: 10.1016/j.jemermed.2007.03.010. Epub 2007 Apr 16.

Abstract

Dextromethorphan (DXM) is a common component of combination cold medications that has become a popular drug of abuse for young adults. Abusers of DXM have developed a simple acid-base extraction technique to "free-base," or extract, the DXM from the unwanted guaifenesin, coloring agents, sweeteners, and alcohol that are typically included in combination cold preparations. We report a case of DXM overdose after ingestion of this purified "Crystal Dex" and discuss the "Agent Lemon" and single-phase extraction techniques that are used to free-base the dextromethorphan.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antitussive Agents / chemistry*
  • Antitussive Agents / poisoning*
  • Chemical Fractionation / methods*
  • Dextromethorphan / chemistry*
  • Dextromethorphan / poisoning*
  • Drug Overdose
  • Guaifenesin / chemistry
  • Humans
  • Male
  • Solvents / chemistry
  • Substance-Related Disorders*

Substances

  • Antitussive Agents
  • Solvents
  • Guaifenesin
  • Dextromethorphan