Embolectomy in a rabbit acute arterial occlusion model using a novel electromechanical extraction device

AJNR Am J Neuroradiol. 2007 May;28(5):872-4.

Abstract

A prototype endovascular electromechanical clot-extraction device was fabricated using a combination of shape memory polymer and shape memory nickel-titanium alloy (nitinol). Five embolic vascular occlusions were created in 4 rabbits by injecting thermally coagulated blood through a 4F catheter in the common carotid artery. Angiography immediately after clot injection showed complete or partial occlusion of the common carotid artery. Posttreatment angiography showed complete (2/5), partial (2/5), or no (1/5) restoration of blood flow.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acute Disease
  • Alloys
  • Animals
  • Cerebral Angiography
  • Disease Models, Animal
  • Embolectomy / instrumentation*
  • Embolectomy / methods*
  • Equipment Design
  • Intracranial Embolism / diagnostic imaging
  • Intracranial Embolism / therapy*
  • Polymers
  • Rabbits

Substances

  • Alloys
  • Polymers
  • nitinol