[Bronchial asthma attack with lactic acidosis and hypokalemia in a case receiving high dose inhalation of procaterol hydrochloride]

Nihon Kokyuki Gakkai Zasshi. 2007 Apr;45(4):361-5.
[Article in Japanese]

Abstract

We report a case of bronchial asthma attack with lactic acidosis and hypokalemia in a patient receiving high-dose inhalation of procaterol hydrochloride. A 28-year-old man was transferred to our hospital because of adynamia, nausea and dyspnea. He had used inhaled procaterol hydrochloride with a pressurized metered dose inhaler about 20 times before admission. On admission, there were no signs of shock state or hypoxemia and laboratory data showed hypokalemia, hyperglycemia and metabolic acidosis with elevated anion gap. Lactic acidosis was identified as the reason for the metabolic acidosis with elevated anion gap. Lactic acidosis improved after 12 hours. Lactic acidosis due to high dose inhalation of procaterol hydrochloride was suggested.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acidosis, Lactic / chemically induced*
  • Administration, Inhalation
  • Adrenergic beta-Agonists / administration & dosage
  • Adrenergic beta-Agonists / adverse effects*
  • Adult
  • Asthma / drug therapy*
  • Humans
  • Hypokalemia / chemically induced*
  • Male
  • Procaterol / administration & dosage
  • Procaterol / adverse effects*

Substances

  • Adrenergic beta-Agonists
  • Procaterol