Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: a clinicopathologic study on 313 patients

Eur J Gynaecol Oncol. 2007;28(2):95-7.

Abstract

Objective: The aim of this study was to analyse the influence of diabetes mellitus as a prognostic factor for overall survival in endometrial cancer.

Materials and methods: Charts were reviewed from patients with endometrial carcinoma from 1985 to 2003. Data on clinicopathologic variables, adjuvant treatment, site of recurrence and survival were collected. The chi-square test was used to examine associations between variables. The Kaplan-Meier method was used for survival analysis and Cox's proportional hazards model for multiple regression analysis.

Results: Multivariate analysis revealed that diabetes mellitus, FIGO stage and depth of myometrial invasion were significantly associated with overall survival.

MeSH terms

  • Adult
  • Aged
  • Comorbidity
  • Diabetes Mellitus / epidemiology*
  • Endometrial Neoplasms / epidemiology*
  • Endometrial Neoplasms / pathology*
  • Female
  • Germany / epidemiology
  • Humans
  • Middle Aged
  • Multivariate Analysis
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Prognosis
  • Proportional Hazards Models
  • Retrospective Studies
  • Survival Analysis
  • Women's Health*