Sleep quality in advanced cancer patients

J Psychosom Res. 2007 May;62(5):527-33. doi: 10.1016/j.jpsychores.2006.11.008.

Abstract

Objective: The objective of this study was to evaluate the sleep quality of advanced cancer patients and its relationship with pain, depression, and hopelessness.

Methods: The participants were 102 advanced cancer patients who were on palliative treatment. Patients completed a sleep quality instrument, the Pittsburgh Sleep Quality Index (PSQI); a pain assessment tool, the Greek Brief Pain Inventory; a self-report measure of depression, the Beck Depression Inventory; and, finally, the Beck Hopelessness Scale.

Results: Multiple regression analyses (forward method) have shown that hopelessness (P=.003), "interference of pain with mood" (P<.0005), and strong opioids (P=.010) seemed to influence patients' sleep quality (PSOI). In an additional regression analysis (enter method), the PSQI is significantly related to opioids (P=.013), hopelessness (P=.035), and "interference of pain with mood" (P=.004).

Conclusion: Hopelessness, pain treatment, and "interference of pain with mood" may influence the quality of sleep in advanced stages of cancer.

MeSH terms

  • Adult
  • Affect
  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Cross-Sectional Studies
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motivation
  • Neoplasm Staging
  • Neoplasms / epidemiology
  • Neoplasms / pathology
  • Neoplasms / psychology*
  • Neoplasms / therapy
  • Pain Measurement
  • Palliative Care
  • Personality Inventory
  • Sick Role
  • Sleep Deprivation / psychology
  • Sleep Wake Disorders / diagnosis*
  • Sleep Wake Disorders / epidemiology
  • Sleep Wake Disorders / psychology
  • Statistics as Topic