Disseminated classic Kaposi's sarcoma

Clin Transl Oncol. 2007 Apr;9(4):255-7. doi: 10.1007/s12094-007-0048-x.

Abstract

Kaposi's sarcoma (KS) is characterised by proliferation of vascular endothelial and lymphoreticular cells, frequently with a multicentric expression developed from a single node and evolving to multiple cutaneous lumps or plaque-like appearance. Four types of KS with similar histological patterns have been described in terms of their clinical and epidemiological features: classic KS, endemic (African) KS, iatrogenic KS and epidemic (AIDS-related) KS. The differences in clinical features are quite relevant: classic KS is usually limited to the lower extremities; whereas immunodeficiency-related diseases frequently involve several organs. A case of a 67-year-old woman with metastatic KS and unproven immunodeficiency is presented.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibiotics, Antineoplastic
  • Biopsy
  • Doxorubicin / administration & dosage
  • Doxorubicin / therapeutic use
  • Female
  • Follow-Up Studies
  • Herpesvirus 8, Human*
  • Humans
  • Leg / pathology
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary
  • Radiography, Abdominal
  • Radiography, Thoracic
  • Remission Induction
  • Sarcoma, Kaposi* / diagnostic imaging
  • Sarcoma, Kaposi* / drug therapy
  • Sarcoma, Kaposi* / pathology
  • Skin / pathology
  • Skin Neoplasms* / drug therapy
  • Skin Neoplasms* / pathology
  • Splenic Neoplasms / diagnostic imaging
  • Splenic Neoplasms / drug therapy
  • Splenic Neoplasms / secondary
  • Time Factors
  • Tomography, X-Ray Computed

Substances

  • Antibiotics, Antineoplastic
  • Doxorubicin