Detection of the CHEK2 1100delC mutation by MLPA BRCA1/2 analysis: a worthwhile strategy for its clinical applicability in 1100delC low-frequency populations?

Breast Cancer Res Treat. 2008 Feb;107(3):455-7. doi: 10.1007/s10549-007-9555-2. Epub 2007 Apr 26.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Breast Neoplasms / genetics*
  • Checkpoint Kinase 2
  • Female
  • Gene Deletion*
  • Genes, BRCA1*
  • Genes, BRCA2*
  • Humans
  • Mutation*
  • Protein Serine-Threonine Kinases / genetics*

Substances

  • Checkpoint Kinase 2
  • CHEK2 protein, human
  • Protein Serine-Threonine Kinases