Mutations of SYCP3 are rare in infertile Spanish men with meiotic arrest

Juanjo Martínez; Sandra Bonache; Alejandro Carvajal; Lluís Bassas; Sara Larriba

doi:10.1016/j.fertnstert.2006.11.163

Mutations of SYCP3 are rare in infertile Spanish men with meiotic arrest

Fertil Steril. 2007 Oct;88(4):988-9. doi: 10.1016/j.fertnstert.2006.11.163. Epub 2007 Apr 16.

Authors

Juanjo Martínez¹, Sandra Bonache, Alejandro Carvajal, Lluís Bassas, Sara Larriba

Affiliation

¹ Medical and Molecular Genetics Center-Fundació IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

PMID: 17434513
DOI: 10.1016/j.fertnstert.2006.11.163

Abstract

No functional SYCP3 exonic SNP was found in infertile Spanish patients with meiosis arrest, suggesting that SYCP3 mutations very likely are not relevant in Spain in genetic susceptibility to meiosis arrest, just as in other studied European populations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Cycle Proteins
DNA-Binding Proteins
Humans
Infertility, Male / genetics*
Male
Meiosis*
Nuclear Proteins / genetics*
Polymorphism, Single Nucleotide*
Spain
Synaptonemal Complex / genetics

Substances

Cell Cycle Proteins
DNA-Binding Proteins
Nuclear Proteins
SYCP3 protein, human