Optical coherence tomography following photodynamic therapy with verteporfin for subfoveal predominantly classic choroidal neovascularization

Ann Ophthalmol (Skokie). 2006 Summer;38(2):121-5. doi: 10.1385/ao:38:2:121.

Abstract

We characterized the changes in optical coherence tomography following photodynamic therapy (PDT) for subfoveal predominantly classic choroidal neovascularization (CNV) in 26 eyes before, 1 week after, and 3 months after treatment. There appears to be a temporal decrease in central retinal thickness, increase in central retinal pigment epithelium/CNV complex thickness, and decrease in subretinal fluid following PDT, making it a useful adjunct in the management of CNV due to of age-related macular degeneration.

MeSH terms

  • Aged
  • Choroidal Neovascularization / diagnosis*
  • Choroidal Neovascularization / drug therapy*
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / physiopathology
  • Exudates and Transudates / metabolism
  • Fovea Centralis
  • Humans
  • Macular Degeneration / complications
  • Macular Edema / diagnosis
  • Macular Edema / etiology
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Pigment Epithelium of Eye / pathology
  • Porphyrins / therapeutic use*
  • Retina / metabolism
  • Retina / pathology
  • Time Factors
  • Tomography, Optical Coherence*
  • Treatment Outcome
  • Verteporfin
  • Visual Acuity

Substances

  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin