Changes in wound field lipids in rat skin

V L Kozel'tsev; T V Volodina; A N Pankrushina; V V Guseva; N V Kostyuk

doi:10.1007/s10517-006-0401-z

Changes in wound field lipids in rat skin

Bull Exp Biol Med. 2006 Oct;142(4):493-4. doi: 10.1007/s10517-006-0401-z.

[Article in English, Russian]

Authors

V L Kozel'tsev¹, T V Volodina, A N Pankrushina, V V Guseva, N V Kostyuk

Affiliation

¹ Vilar Center of Biomedical Technologies, Moscow.

PMID: 17415446
DOI: 10.1007/s10517-006-0401-z

Abstract

Intricate dynamics of lipid transformations was detected in rat skin wound field during regeneration. The content of lipids increased in the granulation fibrous tissue during the early period of regeneration and decreased later. On day 23 the regeneration process was over, the formed scar tissue differed from intact skin by the content of many lipid fractions. in the crust and skin sites adjacent to the wound the regeneration was associated with significant changes in the lipid composition.

MeSH terms

Animals
Cholesterol / metabolism
Cholesterol Esters / metabolism
Diglycerides / metabolism
Fatty Acids, Nonesterified / metabolism
Lipids / physiology*
Male
Phospholipids / metabolism
Rats
Rats, Wistar
Regeneration
Skin / injuries*
Skin / physiopathology
Skin Physiological Phenomena
Triglycerides / metabolism
Wounds and Injuries / physiopathology*

Substances

Cholesterol Esters
Diglycerides
Fatty Acids, Nonesterified
Lipids
Phospholipids
Triglycerides
Cholesterol