Myasthenia gravis in ectopic thymoma presenting as pleural masses

Lung Cancer. 2007 Jul;57(1):115-7. doi: 10.1016/j.lungcan.2007.01.035. Epub 2007 Mar 26.

Abstract

Multiple pleural masses were found in a 52-year-old female suggesting malignant mesothelioma or pleural metastasis from other malignancy. Unexpectedly, ectopic thymoma was diagnosed by percutaneous needle biopsy and subsequent myasthenia gravis developed during admission. Although ectopic thymoma in pleura is unusual, it should be considered as one of the possible etiologies causing diffuse pleural masses.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Cholinesterase Inhibitors / therapeutic use
  • Choristoma / diagnosis
  • Choristoma / pathology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Keratin-19 / metabolism
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology*
  • Mesothelioma / diagnosis
  • Mesothelioma / diagnostic imaging
  • Mesothelioma / pathology*
  • Middle Aged
  • Myasthenia Gravis / complications*
  • Myasthenia Gravis / therapy*
  • Neoplasm Metastasis / diagnostic imaging
  • Neoplasm Metastasis / pathology
  • Pleural Neoplasms / diagnosis
  • Pleural Neoplasms / diagnostic imaging
  • Pleural Neoplasms / pathology*
  • Pyridostigmine Bromide / therapeutic use
  • Radiography
  • T-Lymphocytes / pathology
  • Thymoma / diagnostic imaging
  • Thymoma / pathology*
  • Thymoma / surgery
  • Thymus Gland*
  • Thymus Neoplasms / diagnostic imaging
  • Thymus Neoplasms / pathology*
  • Thymus Neoplasms / surgery
  • Treatment Outcome

Substances

  • Cholinesterase Inhibitors
  • Keratin-19
  • Pyridostigmine Bromide