Surgical margins in radical prostatectomy: a comparison between retropubic and laparoscopic surgery

Int Urol Nephrol. 2007;39(3):865-9. doi: 10.1007/s11255-006-9128-z. Epub 2007 Mar 15.

Abstract

Objectives: To compare positive surgical margins in both radical retropubic prostatectomies and laparoscopic surgery in two reference centres in Brazil.

Materials and methods: One hundred and seventy nine pathological studies from patients, who underwent radical prostatectomy due to prostate adenocarcinoma, 89 submitted to retropubic surgery and 90 to laparoscopic surgery, were analyzed. Inclusion criteria Patients with PSA </=15 ng/ml, and a Gleason score </=7 at the prostate biopsy, maximum T2 clinical staging.

Results: There has been surgical margin compromising in 41.57% of the patients submitted to retropubic radical prostatectomy (RRP), 34.21% of which were at pT2 stage and 84.61% were at pT3 stage. In patients submitted to laparoscopic radical prostatectomy (LRP) positive surgical margin was found at 24.44% of the cases: 20.98% of which were at pT2 stage and 55.55% at pT3 stage.

Conclusions: In the analyzed samples, proportion of positive surgical margin was higher in RRP than in LRP (P = 0.023). A higher number of patients on a randomized prospective study would be necessary for a better comparison between the groups.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery*
  • Aged
  • Humans
  • Laparoscopy*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prostatectomy / methods*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery*