Hydrophobic, organically-modified silica gels enhance the secondary structure of encapsulated apomyoglobin

Chem Commun (Camb). 2007 Mar 28:(12):1266-8. doi: 10.1039/b617078a. Epub 2007 Jan 11.

Abstract

Insertion of hydrophobic groups in a silica matrix, by addition of propyl- or trifluoropropyltrimethoxysilane, leads to a surprising increase in the helical content of apomyoglobin following encapsulation by the sol-gel technique.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Apoproteins / chemistry*
  • Myoglobin / chemistry*
  • Protein Structure, Secondary
  • Silica Gel
  • Silicon Dioxide / chemistry*

Substances

  • Apoproteins
  • Myoglobin
  • apomyoglobin
  • Silica Gel
  • Silicon Dioxide