Fiber bundle estimation and parameterization

Med Image Comput Comput Assist Interv. 2006;9(Pt 2):252-9. doi: 10.1007/11866763_31.

Abstract

Individual white matter fibers cannot be resolved by current magnetic resonance (MR) technology. Many fibers of a fiber bundle will pass through an individual volume element (voxel). Individual visualized fiber tracts are thus the result of interpolation on a relatively coarse voxel grid, and an infinite number of them may be generated in a given volume by interpolation. This paper aims at creating a level set representation of a fiber bundle to describe this apparent continuum of fibers. It further introduces a coordinate system warped to the fiber bundle geometry, allowing for the definition of geometrically meaningful fiber bundle measures.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Artificial Intelligence*
  • Brain / anatomy & histology*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Nerve Fibers, Myelinated / ultrastructure*
  • Neural Pathways / anatomy & histology*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity