Abstract
The antioxidant activity of the methanol extract of Filipendula hexapetala flowers was assessed by the assay for ferric-reducing antioxidant power (FRAP), the assay for DPPH free radical scavenging ability (DPPH) and the assay for the influence of lipid peroxidation in liposomes, induced by Fe(2+)/ascorbate system and measured by the TBA test (LP). The activity of the investigated extract in all test-systems was found to be significant. The principal constituent responsible for the observed effects was isolated and identified as spiraeoside.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / administration & dosage
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Antioxidants / pharmacology*
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Antioxidants / therapeutic use
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Biphenyl Compounds
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Flowers
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Free Radical Scavengers / administration & dosage
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Free Radical Scavengers / pharmacology*
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Free Radical Scavengers / therapeutic use
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Humans
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Lipid Peroxidation / drug effects
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Phytotherapy*
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Picrates / chemistry
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Rosaceae*
Substances
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Antioxidants
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Biphenyl Compounds
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Free Radical Scavengers
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Picrates
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Plant Extracts
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1,1-diphenyl-2-picrylhydrazyl