Chromatid-type aberrations following irradiation in G0 lymphocytes with heavy ions

Mutat Res. 2007 Apr 1;617(1-2):98-103. doi: 10.1016/j.mrfmmm.2007.01.003. Epub 2007 Jan 18.

Abstract

We describe a low level of chromatid-type aberrations which included the relatively rare isochromatid/chromatid triradial in peripheral blood lymphocytes that were irradiated, ostensibly in G0, with accelerated heavy (12)C ions. These were produced only at the energies of 69 MeV/n (34.6 keV/microm), almost absent at the energy of either 58.6 MeV/n (46.07 keV/ microm) or 19.3 MeV/n (97 keV/microm), nor were they found after low-LET X-rays. Mechanisms potentially responsible for their formation are discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Radioisotopes
  • Cells, Cultured / radiation effects
  • Cells, Cultured / ultrastructure
  • Chromatids / radiation effects*
  • Chromatids / ultrastructure
  • Chromosome Aberrations*
  • Chromosomes, Human / radiation effects*
  • Chromosomes, Human / ultrastructure
  • Heavy Ions*
  • Humans
  • Lymphocytes / radiation effects*
  • Lymphocytes / ultrastructure
  • Resting Phase, Cell Cycle / radiation effects
  • X-Rays

Substances

  • Carbon Radioisotopes