Genetic polymorphisms of 17 Y-STRs haplotypes in Chinese Han population residing in Shandong province of China

Jiangwei Yan; Hui Tang; Yacheng Liu; Yuting Jing; Zhangping Jiao; Qingxia Zhang; Junwei Gao; Leipeng Shang; Hua Guo; Jun Yu

doi:10.1016/j.legalmed.2006.11.016

Genetic polymorphisms of 17 Y-STRs haplotypes in Chinese Han population residing in Shandong province of China

Leg Med (Tokyo). 2007 Jul;9(4):196-202. doi: 10.1016/j.legalmed.2006.11.016. Epub 2007 Feb 1.

Authors

Jiangwei Yan¹, Hui Tang, Yacheng Liu, Yuting Jing, Zhangping Jiao, Qingxia Zhang, Junwei Gao, Leipeng Shang, Hua Guo, Jun Yu

Affiliation

¹ Graduate University of Chinese Academy of Sciences, Beijing 100049, China.

PMID: 17275384
DOI: 10.1016/j.legalmed.2006.11.016

Abstract

We have co-amplified (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and Y GATA H4) in a single PCR using the AmpFLSTR Yfiler PCR Amplification system. Allelic frequency distribution and haplotype diversity of 17 Y-chromosomal STR from a sample of 131 unrelated individuals of Chinese Han population living in Shandong province of China were obtained. A total of 129 haplotypes were observed in the 131 individuals studied, of which 127 were unique and two were found in two individuals. The gene diversity values ranged from 0.3560 (DYS391) to 0.9675 (DYS385a,b), The overall haplotype diversity for the 17 Y-STR loci was 0.9998, and the discrimination capacity was 0.9695. These results are compared with those observed in worldwide populations at both the locus and the haplotype level.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Asian People / genetics*
China
Chromosomes, Human, Y / genetics*
Gene Frequency*
Genetics, Population
Haplotypes*
Humans
Male
Microsatellite Repeats*
Phenotype
Polymerase Chain Reaction
Polymorphism, Genetic*
Random Amplified Polymorphic DNA Technique
Sex Factors