Centerline detection and line width estimation are important for many computer vision applications, e.g., road network extraction from high resolution remotely sensed imagery. Radon transform-based linear feature detection has many advantages over other approaches: for example, its robustness in noisy images. However, it usually fails to detect the centerline of a thick line due to the peak selection problem. In this paper, several key issues that affect the centerline detection using the radon transform are investigated. A mean filter is proposed to locate the true peak in the radon image and a profile analysis technique is used to further refine the line parameters. The theta-boundary problem of the radon transform is also discussed and the erroneous line parameters are corrected. Intensive experiments have shown that the proposed methodology is effective in finding the centerline and estimating the line width of thick lines.