Unique composite active site of the hepatitis C virus NS2-3 protease: a new opportunity for antiviral drug design

ChemMedChem. 2007 Mar;2(3):283-4. doi: 10.1002/cmdc.200600285.
No abstract available

MeSH terms

  • Amino Acid Substitution
  • Antiviral Agents / chemistry
  • Antiviral Agents / pharmacology*
  • Binding Sites
  • Catalytic Domain
  • Cysteine Endopeptidases / metabolism*
  • Drug Design*
  • Hepacivirus / drug effects*
  • Hepacivirus / enzymology
  • Models, Molecular
  • Protein Conformation
  • Structure-Activity Relationship

Substances

  • Antiviral Agents
  • Cysteine Endopeptidases
  • NS2-3 protease