Impact of inflammation on ocular immune privilege

Chem Immunol Allergy. 2007:92:155-165. doi: 10.1159/000099266.

Abstract

The immune-privileged status of the anterior chamber of the eye is altered in experimentally induced intraocular inflammation and in the pigment dispersion syndrome of DBA/2J mice. However, the eye has developed multiple mechanisms to maintain ocular immune privilege even in the presence of intraocular inflammation.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Anterior Chamber / immunology
  • Autoimmune Diseases / immunology
  • Eye / immunology*
  • Eye / innervation
  • Humans
  • Immune Tolerance*
  • Mice
  • Ovalbumin / immunology
  • Transforming Growth Factor beta / physiology
  • Uveitis / immunology*

Substances

  • Transforming Growth Factor beta
  • Ovalbumin