Macropodumines D and E, two new alkaloids with unusual skeletons from Daphniphyllum macropodum Miq

Org Lett. 2007 Feb 1;9(3):477-80. doi: 10.1021/ol062828h.

Abstract

[structure: see text] Two new complex polycyclic alkaloids, macropodumines D (1) and E (2), both possessing unprecedented skeletons, along with four known related alkaloids, were isolated from the leaves and barks of Daphniphyllum macropodum Miq. The structures including the relative stereochemistry of new compounds 1 and 2 were elucidated on the basis of detailed spectroscopic data analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification
  • Alkaloids / pharmacology
  • Magnoliopsida / chemistry*
  • Molecular Structure
  • Plant Bark / chemistry
  • Plant Leaves / chemistry
  • Plants, Medicinal*
  • Polycyclic Compounds / chemistry
  • Polycyclic Compounds / isolation & purification*
  • Polycyclic Compounds / pharmacology

Substances

  • Alkaloids
  • Polycyclic Compounds
  • macropodumine D
  • macropodumine E