Maternal morbidity following routine second trimester genetic amniocentesis

Fetal Diagn Ther. 2007;22(3):226-8. doi: 10.1159/000098723. Epub 2007 Jan 17.

Abstract

Two cases of septic complications of routine second trimester amniocentesis are presented. The first case is a 37-year-old gravida suffering from ulcerative colitis who was admitted for amniocentesis in the 18th week of her third pregnancy. An uncomplicated transabdominal amniocentesis was performed using a sterile technique and ultrasound guidance. Twenty-eight hours later the patient had a septic abortion and sepsis. The second case is a 34-year-old gravida in the 24th week of her pregnancy who was admitted with amnionitis 10 h after an uncomplicated amniocentesis, and subsequently had a septic abortion. A high index of suspicion and rapid intervention were crucial in both cases.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Septic / etiology
  • Adult
  • Amniocentesis / adverse effects*
  • Escherichia coli Infections / etiology
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / etiology*
  • Pregnancy Trimester, Second
  • Sepsis / etiology*
  • Staphylococcal Infections / etiology
  • Staphylococcus epidermidis