Characterizing the structure and dynamics of folded oligomers: Pulsed ESR studies of peptoid helices

Chem Commun (Camb). 2007 Jan 28:(4):377-9. doi: 10.1039/b612198e. Epub 2006 Dec 7.

Abstract

Helical peptoid oligomers were synthesized in which the positions of nitroxide radical spin probes along the backbone were systematically varied, allowing evaluation of intra-molecular distances and dynamics by electron spin resonance spectroscopy.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Chromatography, High Pressure Liquid
  • Electron Spin Resonance Spectroscopy
  • Peptoids / chemistry*
  • Peptoids / metabolism*
  • Protein Folding*
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Spectrophotometry, Infrared

Substances

  • Peptoids