Objective: To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele.
Design: Case report.
Setting: Urologic infertility clinic in a university hospital.
Patient(s): Male patient presenting with primary infertility.
Intervention(s): Karyotyping, genetic counseling, and microsurgical left varicocelectomy.
Main outcome measure(s): Sperm concentration and motility, chromosomal number and structure.
Result(s): Fluorescence in situ hybridization revealing SMRC 14. Sperm concentration and motility improved after left varicocele repair.
Conclusion(s): A karyotype should be included in the evaluation of severe oligospermia. Although SMRC 14 may be associated with fertility problems, repair of a coexisting varicocele should be considered in these patients.