Abstract
Twenty isolates resistant to seven quinolones were isolated from major rivers in Korea. All isolates had three mutations, Ser83-->Leu and Asp87-->Asn in GyrA and Ser80-->Ile or Ser80-->Arg in ParC and three isolates had an additional mutation Glu84-->Gly or Glu84-->Val in ParC. In addition, a clonal spread was not found in these isolates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Infective Agents / pharmacology*
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DNA Topoisomerase IV / genetics
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Drug Resistance, Bacterial*
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Escherichia coli / drug effects*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification*
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Humans
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Korea
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Microbial Sensitivity Tests
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Mutation
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Quinolones / pharmacology*
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Rivers / microbiology*
Substances
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Anti-Infective Agents
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Quinolones
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DNA Topoisomerase IV