Isolation of quinolone-resistant Escherichia coli found in major rivers in Korea

J Microbiol. 2006 Dec;44(6):680-4.

Abstract

Twenty isolates resistant to seven quinolones were isolated from major rivers in Korea. All isolates had three mutations, Ser83-->Leu and Asp87-->Asn in GyrA and Ser80-->Ile or Ser80-->Arg in ParC and three isolates had an additional mutation Glu84-->Gly or Glu84-->Val in ParC. In addition, a clonal spread was not found in these isolates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Infective Agents / pharmacology*
  • DNA Topoisomerase IV / genetics
  • Drug Resistance, Bacterial*
  • Escherichia coli / drug effects*
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification*
  • Humans
  • Korea
  • Microbial Sensitivity Tests
  • Mutation
  • Quinolones / pharmacology*
  • Rivers / microbiology*

Substances

  • Anti-Infective Agents
  • Quinolones
  • DNA Topoisomerase IV