Four new compounds from the leaves of Acer truncatum

Chem Biodivers. 2006 Jul;3(7):791-8. doi: 10.1002/cbdv.200690081.

Abstract

Four new compounds, 3-(4-hydroxy-3,5-dimethoxyphenyl)propyl formate (1), 2,6-dimethoxy-4-[(1S)-3-methoxypropyl]phenol (2), (1R,2R)-4-[(3R)-3-hydroxybutyl]-3,3,5-trimethylcyclohex-4-ene-1,2-diol (3), and (1S,3R,3aR,6S,7S,9aR)-decahydro-1-(hydroxymethyl)-1,7-dimethyl-3a,7-methano-3aH-cyclopentacyclooctene (4) were isolated from the leaves of Acer truncatum, together with twelve known compounds. Their structures were elucidated on the basis of extensive spectroscopic techniques. The absolute configuration of compound 3 was established by the modified Mosher's method. All compounds were evaluated for antibacterial activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acer / chemistry*
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Bacillus cereus / drug effects
  • Cyclohexanols / chemistry*
  • Cyclohexanols / pharmacology
  • Escherichia coli / drug effects
  • Formates / chemistry*
  • Formates / pharmacology
  • Gram-Positive Bacteria / drug effects
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Leaves / chemistry
  • Pyrogallol / analogs & derivatives*
  • Pyrogallol / chemistry
  • Pyrogallol / pharmacology
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / pharmacology

Substances

  • 2,6-dimethoxy-4-(3-methoxypropyl)phenol
  • 3-(4-hydroxy-3,5-dimethoxyphenyl)propyl formate
  • 4-(3-hydroxybutyl)-3,3,5-trimethylcyclohex-4-ene-1,2-diol
  • Anti-Bacterial Agents
  • Cyclohexanols
  • Formates
  • Sesquiterpenes
  • decahydro-1-(hydroxymethyl)-1,7-dimethyl-3a,7-methano-3aH-cyclopentacyclooctene
  • Pyrogallol