Total synthesis of (-)-blepharocalyxin D

Haye Min Ko; Dong Gil Lee; Min Ah Kim; Hak Joong Kim; Jaejoon Park; Myoung Soo Lah; Eun Lee

doi:10.1021/ol0627956

Total synthesis of (-)-blepharocalyxin D

Org Lett. 2007 Jan 4;9(1):141-4. doi: 10.1021/ol0627956.

Authors

Haye Min Ko¹, Dong Gil Lee, Min Ah Kim, Hak Joong Kim, Jaejoon Park, Myoung Soo Lah, Eun Lee

Affiliation

¹ Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.

PMID: 17192105
DOI: 10.1021/ol0627956

Abstract

[reaction: see text] The Prins cyclization strategy was successfully applied in the total synthesis of (-)-blepharocalyxin D, a cytotoxic dimeric diarylheptanoid isolated from Alpinia blepharocalyx.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Crystallography, X-Ray
Models, Molecular
Molecular Structure
Pyrans / chemical synthesis*
Pyrans / chemistry

Substances

Pyrans
blepharocalyxin D