Selective thin-layer chromatography of 4-R-1,2,4-triazoles

Yves Boland; Anne Attout; Jacqueline Marchand-Brynaert; Yann Garcia

doi:10.1016/j.chroma.2006.12.012

Selective thin-layer chromatography of 4-R-1,2,4-triazoles

J Chromatogr A. 2007 Feb 2;1141(1):145-9. doi: 10.1016/j.chroma.2006.12.012. Epub 2006 Dec 26.

Authors

Yves Boland¹, Anne Attout, Jacqueline Marchand-Brynaert, Yann Garcia

Affiliation

¹ Université Catholique de Louvain, Unité de Chimie des Matériaux Inorganiques et Organiques, Département de Chimie, Faculté des Sciences, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium.

PMID: 17189635
DOI: 10.1016/j.chroma.2006.12.012

Abstract

A convenient and selective TLC of 4-R-1,2,4-triazoles (Rtrz) and nitrogen containing aromatic rings is presented (molecules 1-11). This simple revelation method implies a complexation of heterocycles to Co(II) ions on a TLC plate, followed by a subsequent modification of the reduction potential which enables oxidation of Co(II) by permanganate.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Thin Layer
Solutions
Triazoles / chemistry*
Triazoles / isolation & purification*

Substances

Solutions
Triazoles