Similarity of RNA secondary structures

J Comput Chem. 2007 Jan 30;28(2):508-12. doi: 10.1002/jcc.20571.

Abstract

In this article, we propose a relatively similar measure to compare RNA secondary structures. We first transform an RNA secondary structure into a special sequence representation. Then, on the basis of symbolic sequence complexity, we obtain the relative distance of RNA secondary structures. The examination of similarities/dissimilarities of a set of RNA secondary structures at the 3'-terminus of different viruses illustrates the utility of the approach.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Computer Simulation
  • Molecular Sequence Data
  • Nucleic Acid Conformation*
  • Phylogeny
  • RNA / chemistry*
  • Sequence Alignment
  • Viruses / chemistry

Substances

  • RNA